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Cell membrane-bound toll-like receptor-1/2/4/6 monomers and -2 heterodimer inhibit enterovirus 71 replication by activating the antiviral innate response

Host immune activation is critical for enterovirus 71 (EV71) clearance and immunopathogenesis. However, the mechanism of innate immune activation, especially of cell membrane-bound toll-like receptors (TLRs), against EV71 remains unknown. We previously demonstrated that TLR2 and its heterodimer inhi...

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Detalles Bibliográficos
Autores principales: Sun, Ping-Ping, Li, Dan, Su, Meng, Ren, Qing, Guo, Wen-Ping, Wang, Jiang-Li, Du, Luan-Ying, Xie, Guang-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189127/
https://www.ncbi.nlm.nih.gov/pubmed/37207203
http://dx.doi.org/10.3389/fimmu.2023.1187035