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Carrier-free delivery of thymopentin-regulated injectable nanogels via an enhanced cancer immunity cycle against melanoma metastasis

Thymopentin (TP5), a clinically used immunomodulatory pentapeptide, can efficiently promote thymocyte differentiation and influence mature T-cell function, thus playing an essential role in the cancer immunotherapy. However, the excellent water solubility and high IC50 of TP5 result in an uncontroll...

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Detalles Bibliográficos
Autores principales: Ding, Ning, He, Kai, Tian, Hailong, Li, Lei, Li, Qiong, Lu, Shuaijun, Ding, Ke, Liu, Jiaqi, Nice, Edouard C., Zhang, Wei, Huang, Canhua, Tang, Yong, Shen, Zhisen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189275/
https://www.ncbi.nlm.nih.gov/pubmed/37206879
http://dx.doi.org/10.1016/j.mtbio.2023.100645