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Development, efficacy and side effects of antibody‑drug conjugates for cancer therapy (Review)

Antibody-drug conjugates (ADCs) are anticancer drugs that combine cytotoxic small-molecule drugs (payloads) with monoclonal antibodies through a chemical linker and that transfer toxic payloads to tumor cells expressing target antigens. All ADCs are based on human IgG. In 2009, the Food and Drug Adm...

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Detalles Bibliográficos
Autores principales: Sun, Te, Niu, Xueli, He, Qing, Liu, Min, Qiao, Shuai, Qi, Rui-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189422/
https://www.ncbi.nlm.nih.gov/pubmed/37206431
http://dx.doi.org/10.3892/mco.2023.2643