Development, efficacy and side effects of antibody‑drug conjugates for cancer therapy (Review)

Antibody-drug conjugates (ADCs) are anticancer drugs that combine cytotoxic small-molecule drugs (payloads) with monoclonal antibodies through a chemical linker and that transfer toxic payloads to tumor cells expressing target antigens. All ADCs are based on human IgG. In 2009, the Food and Drug Adm...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Te, Niu, Xueli, He, Qing, Liu, Min, Qiao, Shuai, Qi, Rui-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189422/
https://www.ncbi.nlm.nih.gov/pubmed/37206431
http://dx.doi.org/10.3892/mco.2023.2643

Ejemplares similares

Ejemplares similares