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Nanoparticle‐mediated genome editing in single‐cell embryos via peptide nucleic acids

Through preimplantation genetic diagnosis, genetic diseases can be detected during the early stages of embryogenesis, but effective treatments for many of these disorders are lacking. Gene editing could allow for correction of the underlying mutation during embryogenesis to prevent disease pathogene...

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Detalles Bibliográficos
Autores principales: Putman, Rachael, Ricciardi, Adele S., Carufe, Kelly E. W., Quijano, Elias, Bahal, Raman, Glazer, Peter M., Saltzman, W. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189434/
https://www.ncbi.nlm.nih.gov/pubmed/37206203
http://dx.doi.org/10.1002/btm2.10458