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Nanoparticle‐mediated genome editing in single‐cell embryos via peptide nucleic acids
Through preimplantation genetic diagnosis, genetic diseases can be detected during the early stages of embryogenesis, but effective treatments for many of these disorders are lacking. Gene editing could allow for correction of the underlying mutation during embryogenesis to prevent disease pathogene...
Autores principales: | Putman, Rachael, Ricciardi, Adele S., Carufe, Kelly E. W., Quijano, Elias, Bahal, Raman, Glazer, Peter M., Saltzman, W. Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189434/ https://www.ncbi.nlm.nih.gov/pubmed/37206203 http://dx.doi.org/10.1002/btm2.10458 |
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