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Unique osteogenic profile of bone marrow stem cells stimulated in perfusion bioreactor is Rho‐ROCK‐mediated contractility dependent

The fate determination of bone marrow mesenchymal stem/stromal cells (BMSC) is tightly regulated by mechanical cues, including fluid shear stress. Knowledge of mechanobiology in 2D culture has allowed researchers in bone tissue engineering to develop 3D dynamic culture systems with the potential for...

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Detalles Bibliográficos
Autores principales: Yamada, Shuntaro, Yassin, Mohammed A., Torelli, Francesco, Hansmann, Jan, Green, Jeremy B. A., Schwarz, Thomas, Mustafa, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189446/
https://www.ncbi.nlm.nih.gov/pubmed/37206242
http://dx.doi.org/10.1002/btm2.10509