Galactosylated hydroxyl‐polyamidoamine dendrimer targets hepatocytes and improves therapeutic outcomes in a severe model of acetaminophen poisoning‐induced liver failure

Toxicity to hepatocytes caused by various insults including drugs is a common cause of chronic liver failure requiring transplantation. Targeting therapeutics specifically to hepatocytes is often a challenge since they are relatively nonendocytosing unlike the highly phagocytic Kupffer cells in the...

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Detalles Bibliográficos
Autores principales: Porterfield, Joshua E., Sharma, Rishi, Jimenez, Ambar Scarlet, Sah, Nirnath, McCracken, Sean, Zhang, Lucia, An, Hyoung‐Tae, Lee, Seulki, Kannan, Sujatha, Sharma, Anjali, Kannan, Rangaramanujam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189448/
https://www.ncbi.nlm.nih.gov/pubmed/37206223
http://dx.doi.org/10.1002/btm2.10486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189448/
https://www.ncbi.nlm.nih.gov/pubmed/37206223
http://dx.doi.org/10.1002/btm2.10486

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