Megakaryocyte membrane‐wrapped nanoparticles for targeted cargo delivery to hematopoietic stem and progenitor cells

Hematopoietic stem and progenitor cells (HSPCs) are desirable targets for gene therapy but are notoriously difficult to target and transfect. Existing viral vector‐based delivery methods are not effective in HSPCs due to their cytotoxicity, limited HSPC uptake and lack of target specificity (tropism...

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Detalles Bibliográficos
Autores principales: Das, Samik, Harris, Jenna C., Winter, Erica J., Kao, Chen‐Yuan, Day, Emily S., Papoutsakis, Eleftherios Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189472/
https://www.ncbi.nlm.nih.gov/pubmed/37206243
http://dx.doi.org/10.1002/btm2.10456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189472/
https://www.ncbi.nlm.nih.gov/pubmed/37206243
http://dx.doi.org/10.1002/btm2.10456

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