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Megakaryocyte membrane‐wrapped nanoparticles for targeted cargo delivery to hematopoietic stem and progenitor cells
Hematopoietic stem and progenitor cells (HSPCs) are desirable targets for gene therapy but are notoriously difficult to target and transfect. Existing viral vector‐based delivery methods are not effective in HSPCs due to their cytotoxicity, limited HSPC uptake and lack of target specificity (tropism...
Autores principales: | Das, Samik, Harris, Jenna C., Winter, Erica J., Kao, Chen‐Yuan, Day, Emily S., Papoutsakis, Eleftherios Terry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189472/ https://www.ncbi.nlm.nih.gov/pubmed/37206243 http://dx.doi.org/10.1002/btm2.10456 |
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