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Characterization of CPH:SA microparticle‐based delivery of interleukin‐1 alpha for cancer immunotherapy

BACKGROUND: Interleukin‐1 alpha (IL‐1α) is a pro‐inflammatory cytokine that can activate immune effector cells and trigger anti‐tumor immune responses. However, dose‐limiting toxicities including cytokine storm and hypotension has limited its use in the clinic as a cancer therapy. We propose that po...

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Detalles Bibliográficos
Autores principales: Hasibuzzaman, M. M., He, Rui, Khan, Ishrat Nourin, Sabharwal, Rasna, Salem, Aliasger K., Simons‐Burnett, Andrean Llewela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189482/
https://www.ncbi.nlm.nih.gov/pubmed/37206237
http://dx.doi.org/10.1002/btm2.10465