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Characterization of CPH:SA microparticle‐based delivery of interleukin‐1 alpha for cancer immunotherapy
BACKGROUND: Interleukin‐1 alpha (IL‐1α) is a pro‐inflammatory cytokine that can activate immune effector cells and trigger anti‐tumor immune responses. However, dose‐limiting toxicities including cytokine storm and hypotension has limited its use in the clinic as a cancer therapy. We propose that po...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189482/ https://www.ncbi.nlm.nih.gov/pubmed/37206237 http://dx.doi.org/10.1002/btm2.10465 |