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Dichotomous ovarian cancer-initiating potential of Pax8+ cells revealed by a mouse genetic mosaic model

Different cellular compartments within a tissue present distinct cancer-initiating capacities. Current approaches to dissect such heterogeneity require cell-type-specific genetic tools based on a well-understood lineage hierarchy, which are lacking for many tissues. Here, we circumvented this hurdle...

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Detalles Bibliográficos
Autores principales: Zeng, Jianhao, Alvarez-Yela, Astrid Catalina, Casarez, Eli, Jiang, Ying, Wang, Lixin, Kelly, Brianna E., Jenkins, Taylor, Ke, Eugene, Atkins, Kristen A., Janes, Kevin A., Slack-Davis, Jill K., Zong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189502/
https://www.ncbi.nlm.nih.gov/pubmed/37207276
http://dx.doi.org/10.1016/j.isci.2023.106742