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Dichotomous ovarian cancer-initiating potential of Pax8+ cells revealed by a mouse genetic mosaic model
Different cellular compartments within a tissue present distinct cancer-initiating capacities. Current approaches to dissect such heterogeneity require cell-type-specific genetic tools based on a well-understood lineage hierarchy, which are lacking for many tissues. Here, we circumvented this hurdle...
Autores principales: | Zeng, Jianhao, Alvarez-Yela, Astrid Catalina, Casarez, Eli, Jiang, Ying, Wang, Lixin, Kelly, Brianna E., Jenkins, Taylor, Ke, Eugene, Atkins, Kristen A., Janes, Kevin A., Slack-Davis, Jill K., Zong, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189502/ https://www.ncbi.nlm.nih.gov/pubmed/37207276 http://dx.doi.org/10.1016/j.isci.2023.106742 |
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