Cargando…

Evaluation of Nonmodified Wireframe DNA Origami for Acute Toxicity and Biodistribution in Mice

[Image: see text] Wireframe DNA origami can be used to fabricate virus-like particles for a range of biomedical applications, including the delivery of nucleic acid therapeutics. However, the acute toxicity and biodistribution of these wireframe nucleic acid nanoparticles (NANPs) have not been previ...

Descripción completa

Detalles Bibliográficos
Autores principales: Wamhoff, Eike-Christian, Knappe, Grant A., Burds, Aurora A., Du, Rebecca R., Neun, Barry W., Difilippantonio, Simone, Sanders, Chelsea, Edmondson, Elijah F., Matta, Jennifer L., Dobrovolskaia, Marina A., Bathe, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189729/
https://www.ncbi.nlm.nih.gov/pubmed/37040258
http://dx.doi.org/10.1021/acsabm.3c00155