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Evaluation of Nonmodified Wireframe DNA Origami for Acute Toxicity and Biodistribution in Mice
[Image: see text] Wireframe DNA origami can be used to fabricate virus-like particles for a range of biomedical applications, including the delivery of nucleic acid therapeutics. However, the acute toxicity and biodistribution of these wireframe nucleic acid nanoparticles (NANPs) have not been previ...
Autores principales: | Wamhoff, Eike-Christian, Knappe, Grant A., Burds, Aurora A., Du, Rebecca R., Neun, Barry W., Difilippantonio, Simone, Sanders, Chelsea, Edmondson, Elijah F., Matta, Jennifer L., Dobrovolskaia, Marina A., Bathe, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189729/ https://www.ncbi.nlm.nih.gov/pubmed/37040258 http://dx.doi.org/10.1021/acsabm.3c00155 |
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