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Direct Nanopore Sequencing of Individual Full Length tRNA Strands
[Image: see text] We describe a method for direct tRNA sequencing using the Oxford Nanopore MinION. The principal technical advance is custom adapters that facilitate end-to-end sequencing of individual transfer RNA (tRNA) molecules at subnanometer precision. A second advance is a nanopore sequencin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189790/ https://www.ncbi.nlm.nih.gov/pubmed/34618430 http://dx.doi.org/10.1021/acsnano.1c06488 |