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APOL1 and the risk of adverse renal outcomes in patients of African ancestry with systemic lupus erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) disproportionately affects individuals of African ancestry (AA) compared to European ancestry (EA). In the general population, high risk (HR) variants in the apolipoprotein L1 (APOL1) gene increase the risk of renal and hypertensive disorders in individ...

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Detalles Bibliográficos
Autores principales: Chung, Cecilia P, Karakoc, Gul, Dickson, Alyson, Liu, Ge, Gamboa, Jorge L, Mosley, Jonathan D, Cox, Nancy J, Kawai, Vivian K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189827/
https://www.ncbi.nlm.nih.gov/pubmed/37105192
http://dx.doi.org/10.1177/09612033231172660