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Blockage of retinoic acid signaling via RARγ suppressed the proliferation of pancreatic cancer cells by arresting the cell cycle progression of the G1-S phase

BACKGROUND: Our study and several studies have reported that in some cancers, including pancreatic ductal adenocarcinoma (PDAC), the expression of squamous lineage markers, such as esophagus-tissue-specific genes, correlated with a poor prognosis. However, the mechanism by which the acquisition of s...

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Detalles Bibliográficos
Autores principales: Yamakawa, Kohei, Koyanagi-Aoi, Michiyo, Machinaga, Akihito, Kakiuchi, Nobuyuki, Hirano, Tomonori, Kodama, Yuzo, Aoi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189913/
https://www.ncbi.nlm.nih.gov/pubmed/37198667
http://dx.doi.org/10.1186/s12935-023-02928-4