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Targeting NRF2 uncovered an intrinsic susceptibility of acute myeloid leukemia cells to ferroptosis

Drug resistance and poor treatment response are major obstacles to the effective treatment of acute myeloid leukemia (AML). A deeper understanding of the mechanisms regulating drug resistance and response genes in AML is therefore urgently needed. Our previous research has highlighted the important...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Zhong, Shuxin, Qiu, Kangjie, Chen, Xi, Wu, Weiyue, Zheng, Jiamian, Liu, Yanwen, Wu, Haolong, Fan, Shiyun, Nie, Dingrui, Wang, Xianfeng, Yu, Zhi, Liao, Ziwei, Zhong, Mengjun, Li, Yangqiu, Zeng, Chengwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189915/
https://www.ncbi.nlm.nih.gov/pubmed/37198609
http://dx.doi.org/10.1186/s40164-023-00411-4