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CysPresso: a classification model utilizing deep learning protein representations to predict recombinant expression of cysteine-dense peptides

BACKGROUND: Cysteine-dense peptides (CDPs) are an attractive pharmaceutical scaffold that display extreme biochemical properties, low immunogenicity, and the ability to bind targets with high affinity and selectivity. While many CDPs have potential and confirmed therapeutic uses, synthesis of CDPs i...

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Detalles Bibliográficos
Autores principales: Ouellet, Sébastien, Ferguson, Larissa, Lau, Angus Z., Lim, Tony K. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189939/
https://www.ncbi.nlm.nih.gov/pubmed/37193950
http://dx.doi.org/10.1186/s12859-023-05327-8