Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology

Aging is the main risk factor for Alzheimer’s disease (AD) and other neurodegenerative pathologies, but the molecular and cellular changes underlying pathological aging of the nervous system are poorly understood. AD pathology seems to correlate with the appearance of cells that become senescent due...

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Detalles Bibliográficos
Autores principales: Suelves, Nuria, Saleki, Shirine, Ibrahim, Tasha, Palomares, Debora, Moonen, Sebastiaan, Koper, Marta J., Vrancx, Céline, Vadukul, Devkee M., Papadopoulos, Nicolas, Viceconte, Nikenza, Claude, Eloïse, Vandenberghe, Rik, von Arnim, Christine A. F., Constantinescu, Stefan N., Thal, Dietmar Rudolf, Decottignies, Anabelle, Kienlen-Campard, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189946/
https://www.ncbi.nlm.nih.gov/pubmed/37198698
http://dx.doi.org/10.1186/s40478-023-01578-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189946/
https://www.ncbi.nlm.nih.gov/pubmed/37198698
http://dx.doi.org/10.1186/s40478-023-01578-x

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