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Polymorphism in autophagy-related genes LRP1 and CAPZA1 may promote gastric mucosal atrophy

BACKGROUND: Helicobacter pylori secretes cytotoxin-associated gene A (CagA) into the gastric epithelium, causing gastric mucosal atrophy (GMA) and gastric cancer. In contrast, host cells degrade CagA via autophagy. However, the association between polymorphisms in autophagy-related genes and GMA mus...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Naoyuki, Sakaguchi, Takuki, Isomoto, Hajime, Inamine, Tatsuo, Tsukamoto, Ryoya, Fukuda, Daisuke, Ohnita, Ken, Kanda, Tsutomu, Matsushima, Kayoko, Hirayama, Tatsuro, Yashima, Kazuo, Tsukamoto, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189954/
https://www.ncbi.nlm.nih.gov/pubmed/37198664
http://dx.doi.org/10.1186/s41021-023-00274-5