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Polymorphism in autophagy-related genes LRP1 and CAPZA1 may promote gastric mucosal atrophy
BACKGROUND: Helicobacter pylori secretes cytotoxin-associated gene A (CagA) into the gastric epithelium, causing gastric mucosal atrophy (GMA) and gastric cancer. In contrast, host cells degrade CagA via autophagy. However, the association between polymorphisms in autophagy-related genes and GMA mus...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189954/ https://www.ncbi.nlm.nih.gov/pubmed/37198664 http://dx.doi.org/10.1186/s41021-023-00274-5 |