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PD-L1 stimulation can promote proliferation and survival of leukemic cells by influencing glucose and fatty acid metabolism in acute myeloid leukemia

BACKGROUND: Leukemic cell metabolism plays significant roles in their proliferation and survival. These metabolic adaptations are under regulation by different factors. Programmed Death Ligand -1 (CD-274) is one of the immune checkpoint ligands that do not only cause the immune escape of cancer cell...

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Detalles Bibliográficos
Autores principales: Soltani, Mojdeh, Ghanadian, Mustafa, Ghezelbash, Behrooz, Shokouhi, Abolfazl, Zamyatnin, Andrey A., Bazhin, Alexandr V., Ganjalikhani-Hakemi, Mazdak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190001/
https://www.ncbi.nlm.nih.gov/pubmed/37193972
http://dx.doi.org/10.1186/s12885-023-10947-7