In planta deglycosylation improves the SARS-CoV-2 neutralization activity of recombinant ACE2-Fc

SARS-CoV-2 infects human cells via binding of the viral spike glycoprotein to its main cellular receptor, angiotensin-converting enzyme 2 (ACE2). The spike protein-ACE2 receptor interaction is therefore a major target for the development of therapeutic or prophylactic drugs to combat coronavirus inf...

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Detalles Bibliográficos
Autores principales: Izadi, Shiva, Vavra, Ulrike, Melnik, Stanislav, Grünwald-Gruber, Clemens, Föderl-Höbenreich, Esther, Sack, Markus, Zatloukal, Kurt, Glössl, Josef, Stöger, Eva, Mach, Lukas, Castilho, Alexandra, Strasser, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190127/
https://www.ncbi.nlm.nih.gov/pubmed/37207124
http://dx.doi.org/10.3389/fbioe.2023.1180044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190127/
https://www.ncbi.nlm.nih.gov/pubmed/37207124
http://dx.doi.org/10.3389/fbioe.2023.1180044

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