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B cells require licensing by dendritic cells to serve as primary antigen-presenting cells for plasmid DNA

DNA vaccines have been an attractive approach for treating cancer patients, however have demonstrated modest immunogenicity in human clinical trials. Dendritic cells (DCs) are known to cross-present DNA-encoded antigens expressed in bystander cells. However, we have previously reported that B cells,...

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Detalles Bibliográficos
Autores principales: Rastogi, Ichwaku, McNeel, Douglas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190194/
https://www.ncbi.nlm.nih.gov/pubmed/37205983
http://dx.doi.org/10.1080/2162402X.2023.2212550