Cargando…

Systematic Evaluation of Pharmacokinetic Models for Model-Informed Precision Dosing of Meropenem in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy

The altered pharmacokinetics of renally cleared drugs such as meropenem in critically ill patients receiving continuous renal replacement therapy (CRRT) might impact target attainment. Model-informed precision dosing (MIPD) is applied to individualize meropenem dosing. However, most population pharm...

Descripción completa

Detalles Bibliográficos
Autores principales: Schatz, Lea Marie, Brinkmann, Alexander, Röhr, Anka, Frey, Otto, Greppmair, Sebastian, Weinelt, Ferdinand, Zoller, Michael, Scharf, Christina, Hempel, Georg, Liebchen, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190255/
https://www.ncbi.nlm.nih.gov/pubmed/37125925
http://dx.doi.org/10.1128/aac.00104-23