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Systematic Evaluation of Pharmacokinetic Models for Model-Informed Precision Dosing of Meropenem in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy
The altered pharmacokinetics of renally cleared drugs such as meropenem in critically ill patients receiving continuous renal replacement therapy (CRRT) might impact target attainment. Model-informed precision dosing (MIPD) is applied to individualize meropenem dosing. However, most population pharm...
Autores principales: | Schatz, Lea Marie, Brinkmann, Alexander, Röhr, Anka, Frey, Otto, Greppmair, Sebastian, Weinelt, Ferdinand, Zoller, Michael, Scharf, Christina, Hempel, Georg, Liebchen, Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190255/ https://www.ncbi.nlm.nih.gov/pubmed/37125925 http://dx.doi.org/10.1128/aac.00104-23 |
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