Membrane Potential-Dependent Uptake of Cationic Oligoimidazolium Mediates Bacterial DNA Damage and Death

The treatment of bacterial infections is becoming increasingly challenging with the emergence of antimicrobial resistance. Thus, the development of antimicrobials with novel mechanisms of action is much needed. Previously, we designed several cationic main-chain imidazolium compounds and identified...

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Detalles Bibliográficos
Autores principales: Yong, Melvin, Kok, Zhi Y., Koh, Chong H., Zhong, Wenbin, Ng, Justin TY., Mu, Yuguang, Chan-Park, Mary B., Gan, Yunn-Hwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190574/
https://www.ncbi.nlm.nih.gov/pubmed/37125913
http://dx.doi.org/10.1128/aac.00355-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190574/
https://www.ncbi.nlm.nih.gov/pubmed/37125913
http://dx.doi.org/10.1128/aac.00355-23

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