DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting KEAP1‐Mediated NRF2 Ubiquitination

Chemoresistance is the main obstacle in osteosarcoma (OS) treatment; however, the underlying mechanism remains unclear. In this study, it is discovered that DDRGK domain‐containing protein 1 (DDRGK1) plays a fundamental role in chemoresistance induced in OS. Bioinformatic and tissue analyses indicat...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xin, Zhou, Tangjun, Yang, Xiao, Cao, Xiankun, Jin, Gu, Zhang, Pu, Guo, Jiadong, Rong, Kewei, Li, Baixing, Hu, Yibin, Liu, Kexin, Ma, Peixiang, Qin, An, Zhao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190621/
https://www.ncbi.nlm.nih.gov/pubmed/36965071
http://dx.doi.org/10.1002/advs.202204438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190621/
https://www.ncbi.nlm.nih.gov/pubmed/36965071
http://dx.doi.org/10.1002/advs.202204438

Ejemplares similares