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Structures of a Mobile Intron Retroelement Poised to Attack Its Structured DNA Target

Group II introns are ribozymes that catalyze their self-excision and function as retroelements that invade DNA. As retrotransposons, group II introns form ribonucleoprotein complexes that roam the genome, integrating by reversal of forward splicing. Here we show that retrotransposition is achieved b...

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Detalles Bibliográficos
Autores principales: Chung, Kevin, Xu, Ling, Chai, Pengxin, Peng, Junhui, Devarkar, Swapnil C., Pyle, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190682/
https://www.ncbi.nlm.nih.gov/pubmed/36356138
http://dx.doi.org/10.1126/science.abq2844