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Molecular dynamics simulation‐guided toehold mediated strand displacement probe for single‐nucleotide variants detection

Single nucleotide variant (SNV) has become an emerging biomarker for various diseases such as cancers and infectious diseases. Toehold‐mediated strand displacement (TMSD), the core reaction of DNA nanotechnology, has been widely leveraged to identify SNVs. However, inappropriate choice of mismatch l...

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Detalles Bibliográficos
Autores principales: Zhang, Linghao, Chen, Jing, He, Mengya, Su, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190925/
https://www.ncbi.nlm.nih.gov/pubmed/37324584
http://dx.doi.org/10.1002/EXP.20210265