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Applying single cell multi-omic analyses to understand treatment resistance in pediatric high grade glioma

Despite improvements in cancer patient outcomes seen in the past decade, tumor resistance to therapy remains a major impediment to achieving durable clinical responses. Intratumoral heterogeneity related to genetic, epigenetic, transcriptomic, proteomic, and metabolic differences between individual...

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Detalles Bibliográficos
Autores principales: Murdaugh, Rebecca L., Anastas, Jamie N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191214/
https://www.ncbi.nlm.nih.gov/pubmed/37205910
http://dx.doi.org/10.3389/fphar.2023.1002296