Cargando…

Applying single cell multi-omic analyses to understand treatment resistance in pediatric high grade glioma

Despite improvements in cancer patient outcomes seen in the past decade, tumor resistance to therapy remains a major impediment to achieving durable clinical responses. Intratumoral heterogeneity related to genetic, epigenetic, transcriptomic, proteomic, and metabolic differences between individual...

Descripción completa

Detalles Bibliográficos
Autores principales:	Murdaugh, Rebecca L., Anastas, Jamie N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191214/ https://www.ncbi.nlm.nih.gov/pubmed/37205910 http://dx.doi.org/10.3389/fphar.2023.1002296

Ejemplares similares

Multi-omics analysis reveals CLIC1 as a therapeutic vulnerability of gliomas
por: Wang, Chengcheng, et al.
Publicado: (2023)

Integrated Multi-Omics Maps of Lower-Grade Gliomas
por: Binder, Hans, et al.
Publicado: (2022)

Multi-omics approaches for in-depth understanding of therapeutic mechanism for Traditional Chinese Medicine
por: Zhu, Xue, et al.
Publicado: (2022)

Miya Improves Osteoarthritis Characteristics via the Gut-Muscle-Joint Axis According to Multi-Omics Analyses
por: Xu, Tianyang, et al.
Publicado: (2022)

Elucidating the pharmacodynamic mechanisms of Yuquan pill in T2DM rats through comprehensive multi-omics analyses
por: Lei, Yan, et al.
Publicado: (2023)

DIPG-45. ELONGIN B REGULATES H3K27M CHROMATIN INCORPORATION TO PROMOTE MALIGNANCY IN DIFFUSE MIDLINE GLIOMA
por: Anastas, Jamie, et al.
Publicado: (2023)

Extended Application of Genomic Selection to Screen Multi-Omics Data for the Development of Novel Pyroptosis-Immune Signatures and Predicting Immunotherapy of Glioma
por: Ma, Shuai, et al.
Publicado: (2022)

Editorial: Molecular and multi-omic approaches in understanding cancer biology and anticancer therapies: current perspectives and new challenges
por: Abdel-Wahab, Basel A., et al.
Publicado: (2023)

Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer
por: Fennell, Emily M. J., et al.
Publicado: (2023)

Single-Cell Analyses in the Multi-omics Era
Publicado: (2020)

Understanding Physiology in the Continuum: Integration of Information from Multiple -Omics Levels
por: Kamisoglu, Kubra, et al.
Publicado: (2017)

HGG-53. PROJECT HOPE: “PEDIATRIC AND AYA HIGH-GRADE GLIOMA OMICS PROJECT”- A LONGITUDINAL MOLECULAR LANDSCAPE OF HIGH-GRADE GLIOMAS RESOLVED AT SINGLE-CELL LEVEL
por: Hack, Olivia A, et al.
Publicado: (2020)

Preoperative Changes in Hematological Markers and Predictors of Glioma Grade and Survival
por: Wang, Peng-Fei, et al.
Publicado: (2018)

Multi-Omics Analysis Based on Genomic Instability for Prognostic Prediction in Lower-Grade Glioma
por: Cao, Yudong, et al.
Publicado: (2022)

Estimating the Prognosis of Low-Grade Glioma with Gene Attention Using Multi-Omics and Multi-Modal Schemes
por: Choi, Sanghyuk Roy, et al.
Publicado: (2022)

Editorial: Multi-omics approaches for decoding heterogeneity in cancer immunotherapy
por: Jiang, Aimin, et al.
Publicado: (2023)

Metronomic Four-Drug Regimen Has Anti-tumor Activity in Pediatric Low-Grade Glioma; The Results of a Phase II Clinical Trial
por: Verschuur, Arnauld, et al.
Publicado: (2018)

Rechallenge to Carboplatin in Children with Low Grade Glioma and Carboplatin Hypersensitivity Reactions
por: Ruggiero, Antonio, et al.
Publicado: (2017)

Multi-Omics Approach to Dissect the Mechanisms of Rexinoid Signaling in Myoblast Differentiation
por: Khilji, Saadia, et al.
Publicado: (2021)

Multi-Omics Approach in the Identification of Potential Therapeutic Biomolecule for COVID-19
por: Singh, Rachana, et al.
Publicado: (2021)

Editorial: Antidepressant mechanisms of natural products based on multi-omics technologies
por: Fang, Yichao, et al.
Publicado: (2023)

A Multi-Institutional Experience in Pediatric High-Grade Glioma
por: Walston, Steve, et al.
Publicado: (2015)

Exploring and analysing single cell multi-omics data with VDJView
por: Samir, Jerome, et al.
Publicado: (2020)

Multi-Omics Approaches: The Key to Improving Respiratory Health in People With Cystic Fibrosis?
por: Lee, Andrew J., et al.
Publicado: (2020)

Editorial: Biomolecules Against Coronaviruses: Molecular Aspects, Multi-Omics and Systems Pharmacology
por: Hano, Christophe, et al.
Publicado: (2022)

Therapeutic and prognostic potential of GPCRs in prostate cancer from multi-omics landscape
por: Li, Shiqi, et al.
Publicado: (2022)

Editorial: A new frontier for traditional medicine research—Multi-omics approaches
por: Fu, Xianjun, et al.
Publicado: (2023)

Potential New Therapies for Pediatric Diffuse Intrinsic Pontine Glioma
por: Long, Wenyong, et al.
Publicado: (2017)

Multi-Omics Comparison of the Spontaneous Diabetes Mellitus and Diet-Induced Prediabetic Macaque Models
por: Yang, Zhu, et al.
Publicado: (2021)

Optimizing Antimicrobial Therapy by Integrating Multi-Omics With Pharmacokinetic/Pharmacodynamic Models and Precision Dosing
por: Yow, Hui-Yin, et al.
Publicado: (2022)

A Novel Multi-Omics Analysis Model for Diagnosis and Survival Prediction of Lower-Grade Glioma Patients
por: Wu, Wei, et al.
Publicado: (2022)

LGG-44. Multi-omic analysis reveals integrated signalling networks in paediatric low-grade glioma
por: Woodward, Lewis, et al.
Publicado: (2022)

Pediatric Low-Grade Gliomas
por: Collins, Kelly L., et al.
Publicado: (2020)

Commentary on: “A Multi-Institutional Experience in Pediatric High Grade Glioma”
por: Caffo, Maria
Publicado: (2015)

Multi-Omics Model Applied to Cancer Genetics
por: Pettini, Francesco, et al.
Publicado: (2021)

Anlotinib Alone or in Combination With Temozolomide in the Treatment of Recurrent High-Grade Glioma: A Retrospective Analysis
por: Yang, Qunying, et al.
Publicado: (2021)

The role of hypoxia-related genes in TACE-refractory hepatocellular carcinoma: Exploration of prognosis, immunological characteristics and drug resistance based on onco-multi-OMICS approach
por: Cheng, Xuelian, et al.
Publicado: (2022)

Multi-Omics Reveals Inhibitory Effect of Baicalein on Non-Alcoholic Fatty Liver Disease in Mice
por: Li, Ping, et al.
Publicado: (2022)

Radiosensitization in Pediatric High-Grade Glioma: Targets, Resistance and Developments
por: Metselaar, Dennis S., et al.
Publicado: (2021)

Multi-Omics for the Understanding of Brain Diseases
por: Villa, Chiara, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_uas9rqhnrhp2070kmbkslq1j08