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Integrating machine learning and single-cell trajectories to analyze T-cell exhaustion to predict prognosis and immunotherapy in colon cancer patients

INTRODUCTION: The incidence of colon adenocarcinoma (COAD) has recently increased, and patients with advanced COAD have a poor prognosis due to treatment resistance. Combining conventional treatment with targeted therapy and immunotherapy has shown unexpectedly positive results in improving the prog...

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Detalles Bibliográficos
Autores principales: Shen, Xiaogang, Zuo, Xiaofei, Liang, Liang, Wang, Lin, Luo, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191250/
https://www.ncbi.nlm.nih.gov/pubmed/37207222
http://dx.doi.org/10.3389/fimmu.2023.1162843