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Matrix prior for data transfer between single cell data types in latent Dirichlet allocation

Single cell ATAC-seq (scATAC-seq) enables the mapping of regulatory elements in fine-grained cell types. Despite this advance, analysis of the resulting data is challenging, and large scale scATAC-seq data are difficult to obtain and expensive to generate. This motivates a method to leverage informa...

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Detalles Bibliográficos
Autores principales: Min, Alan, Durham, Timothy, Gevirtzman, Louis, Noble, William Stafford
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191269/
https://www.ncbi.nlm.nih.gov/pubmed/37146053
http://dx.doi.org/10.1371/journal.pcbi.1011049