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Capsular polysaccharide inhibits vaccine-induced O-antigen antibody binding and function across both classical and hypervirulent K2:O1 strains of Klebsiella pneumoniae

Klebsiella pneumoniae presents as two circulating pathotypes: classical K. pneumoniae (cKp) and hypervirulent K. pneumoniae (hvKp). Classical isolates are considered urgent threats due to their antibiotic resistance profiles, while hvKp isolates have historically been antibiotic susceptible. Recentl...

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Detalles Bibliográficos
Autores principales: Wantuch, Paeton L., Knoot, Cory J., Robinson, Lloyd S., Vinogradov, Evgeny, Scott, Nichollas E., Harding, Christian M., Rosen, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191323/
https://www.ncbi.nlm.nih.gov/pubmed/37146068
http://dx.doi.org/10.1371/journal.ppat.1011367