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EV-D68 virus-like particle vaccines elicit cross-clade neutralizing antibodies that inhibit infection and block dissemination

Enterovirus D68 (EV-D68) causes severe respiratory illness in children and can result in a debilitating paralytic disease known as acute flaccid myelitis. No treatment or vaccine for EV-D68 infection is available. Here, we demonstrate that virus-like particle (VLP) vaccines elicit a protective neutr...

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Detalles Bibliográficos
Autores principales: Krug, Peter W., Wang, Lingshu, Shi, Wei, Kong, Wing-Pui, Moss, Daniel L., Yang, Eun Sung, Fisher, Brian E., Morabito, Kaitlyn M., Mascola, John R., Kanekiyo, Masaru, Graham, Barney S., Ruckwardt, Tracy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191429/
https://www.ncbi.nlm.nih.gov/pubmed/37196074
http://dx.doi.org/10.1126/sciadv.adg6076