USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities

USP7, a ubiquitin-specific peptidase (USP), plays an important role in many cellular processes through its catalytic deubiquitination of various substrates. However, its nuclear function that shapes the transcriptional network in mouse embryonic stem cells (mESCs) remains poorly understood. We repor...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Sun, Lingang, Tan, Yijun, Wang, Qi, Luo, Tao, Li, Chenlu, Yao, Nan, Xie, Yuting, Yi, Xiao, Zhu, Yi, Guo, Tiannan, Ji, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191441/
https://www.ncbi.nlm.nih.gov/pubmed/37196079
http://dx.doi.org/10.1126/sciadv.ade3888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191441/
https://www.ncbi.nlm.nih.gov/pubmed/37196079
http://dx.doi.org/10.1126/sciadv.ade3888

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