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USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities
USP7, a ubiquitin-specific peptidase (USP), plays an important role in many cellular processes through its catalytic deubiquitination of various substrates. However, its nuclear function that shapes the transcriptional network in mouse embryonic stem cells (mESCs) remains poorly understood. We repor...
Autores principales: | Liu, Chao, Sun, Lingang, Tan, Yijun, Wang, Qi, Luo, Tao, Li, Chenlu, Yao, Nan, Xie, Yuting, Yi, Xiao, Zhu, Yi, Guo, Tiannan, Ji, Junfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191441/ https://www.ncbi.nlm.nih.gov/pubmed/37196079 http://dx.doi.org/10.1126/sciadv.ade3888 |
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