Transcriptional regulation of Sis1 promotes fitness but not feedback in the heat shock response

The heat shock response (HSR) controls expression of molecular chaperones to maintain protein homeostasis. Previously, we proposed a feedback loop model of the HSR in which heat-denatured proteins sequester the chaperone Hsp70 to activate the HSR, and subsequent induction of Hsp70 deactivates the HS...

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Detalles Bibliográficos
Autores principales: Garde, Rania, Singh, Abhyudai, Ali, Asif, Pincus, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191621/
https://www.ncbi.nlm.nih.gov/pubmed/37158601
http://dx.doi.org/10.7554/eLife.79444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191621/
https://www.ncbi.nlm.nih.gov/pubmed/37158601
http://dx.doi.org/10.7554/eLife.79444

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