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ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization

The actin cytoskeleton is tightly controlled by RhoGTPases, actin binding-proteins and nucleation-promoting factors to perform fundamental cellular functions. We have previously shown that ERK3, an atypical MAPK, controls IL-8 production and chemotaxis (Bogueka et al., 2020). Here, we show in human...

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Detalles Bibliográficos
Autores principales: Bogucka-Janczi, Katarzyna, Harms, Gregory, Coissieux, Marie-May, Bentires-Alj, Mohamed, Thiede, Bernd, Rajalingam, Krishnaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191626/
https://www.ncbi.nlm.nih.gov/pubmed/37057894
http://dx.doi.org/10.7554/eLife.85167