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A high-throughput 3D cantilever array to model airway smooth muscle hypercontractility in asthma

Asthma is often characterized by tissue-level mechanical phenotypes that include remodeling of the airway and an increase in airway tightening, driven by the underlying smooth muscle. Existing therapies only provide symptom relief and do not improve the baseline narrowing of the airway or halt progr...

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Detalles Bibliográficos
Autores principales: Beri, Pranjali, Plunkett, Christopher, Barbara, Joshua, Shih, Chien-Cheng, Barnes, S. Whitney, Ross, Olivia, Choconta, Paula, Trinh, Ton, Gomez, Datzael, Litvin, Bella, Walker, John, Qiu, Minhua, Hammack, Scott, Toyama, Erin Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191677/
https://www.ncbi.nlm.nih.gov/pubmed/37206658
http://dx.doi.org/10.1063/5.0132516