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Clinical utility of SARS-CoV-2 subgenomic RT-PCR in a pediatric quaternary care setting

BACKGROUND: During active transcription, SARS-CoV-2 generates subgenomic regions of viral RNA. While standard SARS-CoV-2 RT-PCR amplifies region(s) of genomic RNA, it cannot distinguish active infection from remnant viral genomic material. However, screening for subgenomic RNA (sgRNA) by RT-PCR may...

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Detalles Bibliográficos
Autores principales: Osborn, Lucas J, Chen, Pei Ying, Flores-Vazquez, Jessica, Mestas, Javier, Salas, Edahrline, Glucoft, Marisa, Smit, Michael A, Costales, Cristina, Dien Bard, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191725/
https://www.ncbi.nlm.nih.gov/pubmed/37210881
http://dx.doi.org/10.1016/j.jcv.2023.105494