Widespread somatic L1 retrotransposition in normal colorectal epithelium

Throughout an individual’s lifetime, genomic alterations accumulate in somatic cells(1–11). However, the mutational landscape induced by retrotransposition of long interspersed nuclear element-1 (L1), a widespread mobile element in the human genome(12–14), is poorly understood in normal cells. Here...

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Detalles Bibliográficos
Autores principales: Nam, Chang Hyun, Youk, Jeonghwan, Kim, Jeong Yeon, Lim, Joonoh, Park, Jung Woo, Oh, Soo A, Lee, Hyun Jung, Park, Ji Won, Won, Hyein, Lee, Yunah, Jeong, Seung-Yong, Lee, Dong-Sung, Oh, Ji Won, Han, Jinju, Lee, Junehawk, Kwon, Hyun Woo, Kim, Min Jung, Ju, Young Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191854/
https://www.ncbi.nlm.nih.gov/pubmed/37165195
http://dx.doi.org/10.1038/s41586-023-06046-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191854/
https://www.ncbi.nlm.nih.gov/pubmed/37165195
http://dx.doi.org/10.1038/s41586-023-06046-z

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