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DNA segment capture by Smc5/6 holocomplexes

Three distinct structural maintenance of chromosomes (SMC) complexes facilitate chromosome folding and segregation in eukaryotes, presumably by DNA loop extrusion. How SMCs interact with DNA to extrude loops is not well understood. Among the SMC complexes, Smc5/6 has dedicated roles in DNA repair an...

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Detalles Bibliográficos
Autores principales: Taschner, Michael, Gruber, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191858/
https://www.ncbi.nlm.nih.gov/pubmed/37012407
http://dx.doi.org/10.1038/s41594-023-00956-2