Cold temperature extends longevity and prevents disease-related protein aggregation through PA28γ-induced proteasomes

Aging is a primary risk factor for neurodegenerative disorders that involve protein aggregation. Because lowering body temperature is one of the most effective mechanisms to extend longevity in both poikilotherms and homeotherms, a better understanding of cold-induced changes can lead to converging...

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Detalles Bibliográficos
Autores principales: Lee, Hyun Ju, Alirzayeva, Hafiza, Koyuncu, Seda, Rueber, Amirabbas, Noormohammadi, Alireza, Vilchez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191861/
https://www.ncbi.nlm.nih.gov/pubmed/37118550
http://dx.doi.org/10.1038/s43587-023-00383-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191861/
https://www.ncbi.nlm.nih.gov/pubmed/37118550
http://dx.doi.org/10.1038/s43587-023-00383-4

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