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Gut-specific telomerase expression counteracts systemic aging in telomerase-deficient zebrafish

Telomere shortening is a hallmark of aging and is counteracted by telomerase. As in humans, the zebrafish gut is one of the organs with the fastest rate of telomere decline, triggering early tissue dysfunction during normal zebrafish aging and in prematurely aged telomerase mutants. However, whether...

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Detalles Bibliográficos
Autores principales: El Maï, Mounir, Bird, Malia, Allouche, Asma, Targen, Seniye, Şerifoğlu, Naz, Lopes-Bastos, Bruno, Guigonis, Jean-Marie, Kang, Da, Pourcher, Thierry, Yue, Jia-Xing, Ferreira, Miguel Godinho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191862/
https://www.ncbi.nlm.nih.gov/pubmed/37142828
http://dx.doi.org/10.1038/s43587-023-00401-5