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Mechanochemically‐Assisted Passerini Reactions: A Practical and Convenient Method for the Synthesis of Novel α‐Acyloxycarboxamide Derivatives

A carboxylic acid, an aldehyde, and an isonitrile were combined in a single step (Passerini reaction) under mechanochemical activation to produce several α‐acyloxycarboxamide derivatives in high to excellent yields within 15 min of milling. Mechanochemistry, when combined with the diversity provided...

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Detalles Bibliográficos
Autores principales: Salami, Sodeeq Aderotimi, Safari, Justin Bazibuhe, Smith, Vincent J., Krause, Rui W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191865/
https://www.ncbi.nlm.nih.gov/pubmed/37198143
http://dx.doi.org/10.1002/open.202200268