Not just protons: Chloride also activates lysosomal acidic hydrolases

Lysosomal hydrolases require an acidic lumen for their optimal activities. In this issue, two independent groups (Wu et al. 2023. J. Cell Biol. https://doi.org/10.1083/jcb.202208155; Zhang et al. 2023. J. Cell. Biol. https://doi.org/10.1083/jcb.202210063) report that hydrolase activation also requir...

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Detalles Bibliográficos
Autores principales: Feng, Xinghua, Liu, Siyu, Xu, Haoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191866/
https://www.ncbi.nlm.nih.gov/pubmed/37191899
http://dx.doi.org/10.1083/jcb.202305007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191866/
https://www.ncbi.nlm.nih.gov/pubmed/37191899
http://dx.doi.org/10.1083/jcb.202305007

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