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Not just protons: Chloride also activates lysosomal acidic hydrolases
Lysosomal hydrolases require an acidic lumen for their optimal activities. In this issue, two independent groups (Wu et al. 2023. J. Cell Biol. https://doi.org/10.1083/jcb.202208155; Zhang et al. 2023. J. Cell. Biol. https://doi.org/10.1083/jcb.202210063) report that hydrolase activation also requir...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191866/ https://www.ncbi.nlm.nih.gov/pubmed/37191899 http://dx.doi.org/10.1083/jcb.202305007 |